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The Retinoids

Biology, Biochemistry, and Disease

Authors: Pascal Dollé, Karen Niederreither Publisher: Wiley Publication date: 2015 Publication language: Angielski Number of pages: 634 Publication formats: EAN: 9781118628270 ISBN: 9781118628270 Category: Biology, life sciences Publisher's index: - Bibliographic note: -


The Retinoids: Biology, Biochemistry, and Disease provides an overview and synthesis of the retinoid molecules, from basic biology to mechanisms of diseases and therapy. Divided into five sections, the book covers retinoic acid signaling from biochemical, genetic, developmental, and clinical perspectives. 

The text is divided into five sections, the first of which examines vitamin A metabolic and enzymatic pathways. Focus then shifts to the role of retinoic acid signaling in development, and then to retinoids and physiological function. The book concludes with chapters on retinoids, disease and therapy.

Comprehensive in scope and written by leading researchers in the field, The Retinoids: Biology, Biochemistry, and Disease will be an essential reference for biologists, biochemists, geneticists and developmental biologists, as well as for clinicians and pharmacists engaged in clinical research involving retinoids.


  • Title Page 6
  • Copyright Page 7
  • Contents 8
  • Contributors 12
  • Preface 16
  • Part I Vitamin A Metabolic and Enzymatic Pathways 22
    • Chapter 1 Vitamin A Metabolism, Storage and Tissue Delivery Mechanisms 24
      • I. Introduction 24
      • II. Vitamin A Metabolism Relevant to its Storage 25
      • III. Vitamin A Storage 31
      • IV. Vitamin A Transport in the Circulation 40
      • V. Integration within the Intact Organism of Vitamin A Metabolism, Storage and Transport 45
      • References 46
      • Acknowledgments 46
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