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Food Allergy: Molecular Basis and Clinical Practice
Authors: M. Ebisawa, B.K. Ballmer-Weber, S. Vieths, R.A. Wood Publisher: S. Karger AG Publication date: 2015 Publication language: Angielski Number of pages: 296 Publication formats: EAN: 9783318023411 ISBN: 9783318023411 Category: Allergies Paediatric medicine Immunology Clinical & internal medicine Medical laboratory testing & techniques Dermatology Otorhinolaryngology (ENT) Dietetics & nutrition Publisher's index: 9783318023411 Bibliographic note: -
TOC
- Cover 2
- Front Matter 5
- Contents 7
- Preface 17
-
Background
19
-
Historical Background, Definitions and Differential Diagnosis
19
- Historical Background 19
- Abstract 19
- Definitions and Differential Diagnosis 21
- Recent History and the Future 23
- References 25
-
Immunological Basis of Food Allergy(IgE-Mediated, Non-IgE-Mediated, and Tolerance)
26
- Abstract 26
- Introduction 26
- IgE-Mediated Food Allergy 27
-
Historical Background, Definitions and Differential Diagnosis
19
- Cover 2
- Front Matter 5
- Contents 7
- Preface 17
-
Background
19
-
Historical Background, Definitions and Differential Diagnosis
19
- Historical Background 19
- Abstract 19
- Definitions and Differential Diagnosis 21
- Recent History and the Future 23
- References 25
-
Immunological Basis of Food Allergy(IgE-Mediated, Non-IgE-Mediated, and Tolerance)
26
- Abstract 26
- Introduction 26
- IgE-Mediated Food Allergy 27
- Non-IgE-Mediated Food Allergy 29
- Mixed-Immune Food Reactions 30
- Oral Tolerance 31
- Conclusion 32
- References 34
-
Food Allergens: Molecular and Immunological Aspects, Allergen Databases and Cross-Reactivity
36
- Abstract 36
- Molecular Features of Food Allergens 37
- Class I Food Allergens/Class II Food Allergens 40
- Resistance to Food Processing and Digestion 41
- Immunological Features of Food Allergens 43
- Cross-Reactivity 44
- References 46
-
Epidemiology: International Point of View, from Childhood to Adults, Food Allergens
48
- Abstract 48
- Epidemiology of Food Allergy 48
- Reported Food Allergy and Epidemiology Study Methodology 49
- Prevalence of Common Food Allergies 50
- Changing Prevalence of Food Allergy 54
- References 54
-
Clinical Aspects
56
-
Food Allergy in Childhood (Infancy to School Age)
56
- Abstract 56
- Introduction 56
- IgE-Mediated (Immediate-Type) Food Allergy 57
- Mixed IgE and Non-IgE-Mediated Food Allergy 60
- Non-IgE-Mediated Food Allergy 62
- Conclusions 66
- References 66
-
Food Allergy in Adolescence and Adulthood
69
- Abstract 69
- Introduction 69
- Food Allergies Due to Cross-Reaction with Inhalant Allergens 70
- Sensitization to Galactose-Alpha-1,3-Galactose and Allergy to Red Meat 72
- Clinical Symptoms 73
- Differential Diagnosis of Food Allergy in Adults 74
- References 75
-
Diagnosis and Management
77
-
Hints for Diagnosis
77
- The Purpose of the Diagnosis 77
- Is It Food Allergy? 77
- Abstract 77
- Which Is the Culprit Food? 79
- Which Allergens Are Involved? 80
- How Much Is Too Much? 80
- Prerequisites for Diagnosis 81
- The Diagnostic Process 81
- Conclusions 84
- References 84
- Who Should Perform the Diagnosis? 84
-
IgE-Related Examination in Food Allergy with Focus on Allergen Components
86
- Abstract 86
- How IgE-Mediated Food Allergy Is Diagnosed 86
- Component-Resolved Diagnostics 87
- Development of a Test for Allergen Components 87
- Heat Stability in Proteins 87
- Species-Specific and Cross-Reactive Proteins 89
- New Allergen Component Test: An Emerging Field of Interest 90
- Temporal Development of Allergen Components 91
- Singleplex versus Multiplex Testing 92
- Skin Prick Test 93
- Basophil Activation Test 93
- Future Perspectives 93
- Correlation of the Skin Prick Test and the Basophil Activation Test with Oral Immunotherapy 94
- References 95
-
Non-IgE-Related Diagnostic Methods(LST, Patch Test)
97
- Abstract 97
- Introduction 97
- Lymphocyte Stimulation Test 98
- Patch Test/Atopy Patch Test 100
- References 102
-
Diagnostic Elimination Diets and Oral Food Provocation
105
- Elimination Diets 105
- Abstract 105
- Introduction 105
- Oral Challenge Testing 106
- Methodology 107
- Challenge Settings and Procedures 108
- Dosing Strategies 110
- Risk and Treatment of Oral Food Challenges 111
- Summary 112
- References 112
-
Pharmacological Management of Acute Food-Allergic Reactions
114
- Abstract 114
- Introduction 114
- Pharmacological Management of IgE-Mediated, Food-Induced Acute Allergic Reactions 116
- Subsequent Management of IgE-Mediated Food-Induced Allergic Reactions 120
- Pharmacological Management of Non-IgE-Mediated Food-Induced Allergic Reactions 121
- Conclusions 122
- References 122
-
Oral Immunotherapy and Potential Treatment
124
- Oral Immunotherapy for Food Allergy 124
- Abstract 124
- Introduction 124
- Clinical Use of Oral Immunotherapy 127
- Novel Treatment for Food Allergy 128
- References 130
- Conclusion 130
- Acknowledgments 130
-
Allergen-Based Food Allergies
132
-
Cow’s Milk Allergy in Children and Adults
132
- Abstract 132
- Introduction 132
- Epidemiology 132
- Clinical Manifestations 133
- Pathogenesis 133
- Allergens 133
- Diagnosis 135
- Treatment of Cow’s Milk Allergy 136
- Natural History 136
- Conclusions 140
- References 140
-
Hen’s Egg Allergy
142
- Introduction 142
- Abstract 142
- Symptoms 143
- Allergenic Components of Egg White 143
- Allergenic Components of Egg Yolk 144
- Diagnosis 144
- Natural History 145
- Management and Therapy 146
- Oral Immunotherapy to Egg Allergy 146
- Clinical Case 147
- Acknowledgments 147
- References 147
-
Peanut and Tree Nut Allergy
149
- Epidemiology 149
- Abstract 149
- Introduction 149
- Clinical Reactions 150
- Age of Presentation or First Reaction to Peanut and Tree Nuts 151
- Co-Allergy to Peanut and Tree Nuts and Allergy to Multiple Tree Nuts 151
- Subsequent Reactions 151
- Resolution of Peanut Allergy 152
- Resolution of Tree Nut Allergy 152
- Peanut and Tree Nut Allergens 152
- Case Study 154
- Tree Nut Allergens 154
- Conclusion 158
- References 159
-
Grain and Legume Allergy
163
- Abstract 163
- Grain (Wheat) Allergies 163
- Legume (Soybean) Allergies 166
- References 168
- Conclusions 168
- Acknowledgments 168
-
Fish and Shellfish Allergy
170
- Introduction 170
- Prevalence 170
- Abstract 170
- Classification of Seafood Species 171
- Clinical Manifestations 172
- Fish and Shellfish Allergens 173
- Allergenic Cross-Reactivity 175
- Differential Diagnosis for Fish and Shellfish Allergy 176
- Natural History and Treatment 177
- Diagnosis 177
- Conclusions 178
- References 178
-
Fruit and Vegetable Allergy
180
- Introduction 180
- Abstract 180
- Epidemiology 181
- Pathogenesis: Allergen Sensitisation 181
- Allergens 184
- Clinical Symptoms 184
- Diagnosis 185
- Management 186
- References 187
-
Disease-Based Food Allergies
189
-
Gastrointestinal Food Allergies
189
- Introduction 189
- Abstract 189
- Clinical Presentation 190
- Diagnostic Evaluation and Differential Diagnosis 194
- Dietary Management 195
- Conclusion 195
- References 196
-
Atopic Eczema and Food Allergy
199
- Prevalence and Natural History of Food Allergies in Atopic Eczema 199
- Abstract 199
- Clinical Reaction Patterns to Foods in Patients with Atopic Eczema 200
- Pathogenesis of Food Allergy in Atopic Eczema 201
- Allergens 201
- Diagnosis of Food Allergy in Atopic Eczema 203
- References 206
-
Anaphylaxis in Food Allergy
209
- Introduction 209
- Abstract 209
- Diagnosis 210
- Laboratory Evaluation 211
- Management of Anaphylaxis 212
- Food-Dependent Exercise-Induced Anaphylaxis 214
- Summary 215
- References 215
-
Eosinophilic Oesophagitis
217
- Abstract 217
- Introduction 217
- Clinical Presentation in Children and Adults 218
- Epidemiology 218
- Mechanisms of Disease 219
- Diagnostic Evaluation 220
- Natural History and Complications 220
- Treatment 221
- Conclusion and Future Directions 223
- References 223
-
Special Topics
227
-
Nutritional Aspects and Diets in Food Allergy
227
- Elimination Diet in Food Allergy Diagnosis 227
- Abstract 227
- Elimination Diet in Food Allergy Management 228
- Loopholes in the Labeling Laws 228
- Changing Paradigms in the Management of Milk and Egg Allergy: Baked Milk and Egg Diet 229
- The Effects of Allergen Avoidance on Nutrition in Children 230
- Feeding and Developmental Needs 234
- Nutritional Impact of Specific Food-Allergic Disorders 234
- Nutritional Issues in Adults with Food Allergy 236
- Summary 237
- References 237
-
Food Allergy: Psychosocial Impact and Public Policy Implications
239
- Abstract 239
- Introduction 239
- Impact of Food Allergy on Daily Life 240
- Food Allergy Knowledge and Attitudes 240
- Current Food Allergy-Related Public Policy 241
- Implications and Future Directions 242
- References 243
-
Worldwide Food Allergy Labeling and Detection of Allergens in Processed Foods
245
- Abstract 245
- Introduction 245
- Labeling of Allergenic Foods 246
- Ingredient Labeling and Exemptions 249
- Advisory Labeling 249
- Detection of Food Allergen Residues 251
- Conclusion 251
- Quantitative Immunoassay Methods 251
- Qualitative Immunoassay Methods 251
- References 252
-
The Effects of Food Allergy on Quality of Life
253
- Abstract 253
- Introduction 254
- Main Body 256
- Discussion 266
- References 269
- Conclusion 269
-
Prevention of Food Allergy
271
- Introduction 271
- Abstract 271
- Onset of Sensitisation and Food Allergy 272
- Maternal Diet (During Pregnancy and/or Breastfeeding) and the Prevention of Food Allergy 272
- Methodological Challenges 272
- Complementary Infant Feeding and the Prevention of Food Allergy 272
- Combined Maternal and Infant Dietary Measures and the Prevention of Food Allergy 275
- Routes of Sensitisation 276
- Oral Tolerance Induction 276
- Conclusions 277
- Unpasteurised Milk, Probiotics and Prebiotics 277
- Nutritional Supplements 277
- References 278
-
Educational Programmes in Food Allergy
281
- Abstract 281
- Introduction 281
- Individual Dietetic Treatment of Food Allergy 281
- Structured Educational Group Sessions for Patients and Families with Atopic Eczema or Anaphylaxis 282
- Educational Programmes for Atopic Eczema 282
- Educational Program for Anaphylaxis Patients and Families 285
- References 287
- Acknowledgments 288
- Author Index 289
- Subject Index 290
- Cover 297
-
Nutritional Aspects and Diets in Food Allergy
227
-
Gastrointestinal Food Allergies
189
-
Cow’s Milk Allergy in Children and Adults
132
-
Hints for Diagnosis
77
-
Food Allergy in Childhood (Infancy to School Age)
56
-
Historical Background, Definitions and Differential Diagnosis
19