Molecular Nephrology

FOREWORD 6
OPENING REMARKS 7
SPONSORS 8
CONTENTS 10
I. FUNCTION OF BRUSH BORDER MEMBRANE 18
HYDROLYSIS OF NEUROPEPTIDES BY PIG KIDNEY MICROVILLAR PEPTIDASES: THE KEY ROLE OF ENDOPEPTIDASE-24.11 18
IDENTIFICATION OF COMPONENTS OF NA+-D-GLUCOSE COTRANSPORT PROTEINS IN BRUSH-BORDER MEMBRANES FROM RENAL CORTEX 28
RENAL TRANSPORT AND METABOLISM OF CARNOSINE IN THE RAT 36
MODULATION OF RENAL APICAL MEMBRANE FLUIDITY AND Na+-DEPENDENT D-GLUCOSE TRANSPORT BY FATTY ACIDS IN VITRO 42
RENAL METABOLISM OF C-PEPTIDE IN MAN 48
II. TRANSPORT ATPASES AND METABOLITE TRANSPORTING SYSTEMS 58
BIOCHEMICAL PROPERTIES OF THE PROTON TRANSLOCATING ATPase IN RAT KIDNEY CORTEX BRUSH BORDER MEMBRANES: EFFECT OF INHIBITORS, pH 58
ALDOSTERONE-INDEPENDENT EFFECTS OF DIETARY POTASSIUM ON N-ETHYLMALEIMIDESENSITIVE ATPASE IN DISTAL NEPHRON SEGMENTS OF ADRENALEC 66
ELECTROGENIC H+—ATPase AND ANION CONDUCTANCE IN PIG RENAL CORTICAL ENDOCYTOTIC VESICLES 72
INTERACTION BETWEEN TRIIODOTHYRONINE AND ALDOSTERONE IN CONTROL OF KIDNEY Na-K-ATPase 78

FOREWORD 6
OPENING REMARKS 7
SPONSORS 8
CONTENTS 10
I. FUNCTION OF BRUSH BORDER MEMBRANE 18
HYDROLYSIS OF NEUROPEPTIDES BY PIG KIDNEY MICROVILLAR PEPTIDASES: THE KEY ROLE OF ENDOPEPTIDASE-24.11 18
IDENTIFICATION OF COMPONENTS OF NA+-D-GLUCOSE COTRANSPORT PROTEINS IN BRUSH-BORDER MEMBRANES FROM RENAL CORTEX 28
RENAL TRANSPORT AND METABOLISM OF CARNOSINE IN THE RAT 36
MODULATION OF RENAL APICAL MEMBRANE FLUIDITY AND Na+-DEPENDENT D-GLUCOSE TRANSPORT BY FATTY ACIDS IN VITRO 42
RENAL METABOLISM OF C-PEPTIDE IN MAN 48
II. TRANSPORT ATPASES AND METABOLITE TRANSPORTING SYSTEMS 58
BIOCHEMICAL PROPERTIES OF THE PROTON TRANSLOCATING ATPase IN RAT KIDNEY CORTEX BRUSH BORDER MEMBRANES: EFFECT OF INHIBITORS, pH 58
ALDOSTERONE-INDEPENDENT EFFECTS OF DIETARY POTASSIUM ON N-ETHYLMALEIMIDESENSITIVE ATPASE IN DISTAL NEPHRON SEGMENTS OF ADRENALEC 66
ELECTROGENIC H+—ATPase AND ANION CONDUCTANCE IN PIG RENAL CORTICAL ENDOCYTOTIC VESICLES 72
INTERACTION BETWEEN TRIIODOTHYRONINE AND ALDOSTERONE IN CONTROL OF KIDNEY Na-K-ATPase 78
STRUCTURAL BASIS FOR REGULATION OF ACTIVE NaCl TRANSPORT IN THICK ASCENDING LIMB OF HENLES LOOP 86
EVIDENCE FOR A REABSORPTIVE K+ PUMP IN KIDNEYS OF POTASSIUMDEPLETED RATS 92
AFFINITY LABELS AS SUBSTRATES FOR THE ANION TRANSPORT SYSTEMS AT THE CONTRALUMINAL CELL SIDE OF THE RENAL PROXIMAL TUBULE 100
A RAPID METHOD FOR THE RECONSTITUTION OF NEUTRAL AMINO ACID TRANSPORT SYSTEMS FROM OX KIDNEY BRUSH BORDER MEMBRANES 106
KINETICS OF INHIBITION OF TRANSMEMBRANE GLUCOSE TRANSPORT AND OF INSULIN BINDING BY A PEPTIDE ISOLATED FROM UREMIC PLASMA 112
MEDIATED TRANSPORT OF LONG CHAIN FATTY ACIDS BY RAT RENAL BASOLATERAL MEMBRANES AND EVIDENCE FOR ITS REGULATION 118
MAINTENANCE OF DIFFERENTIATED FUNCTION OF THICK ASCENDING LOOP OF HENLE (TALH) CELLS FOLLOWING TRANSFECTION WITH "EARLY REGION D 124
NMR STUDIES ON A RENAL EPITHELIAL CELL LINE: LLC-PK1/CI 4 130
FESPIRSITCN CF NEEHFCN SEXMNIS OF THE DOG: EFFECT OF OUABAIN AND DOCD 136
ELECTROPHYSIOLOGY OF CELL VOLUME REGULATION 148
III. CELL MEMBRANE POTENTIAL AND TRANSPORT PROCESSES 148
EFFECTS OF A 23187, VERAPAMIL, AND QUINIDINE ON ELECTRICAL PROPERTIES OF MADIN-DARBY-CANINE-KIDNEY AND MOUSE STRAIGHT PROXIMAL T 156
EFFECT OF BRADYKININ AND EPINEPHRINE ON ELECTRICAL PROPERTIES OF MADIN-DARBY-CANINE-KIDNEY CELLS 164
INTRACELLULAR Na+ AND K+ ACTIVITIES IN SODIUM MALEATE TREATED FROG KIDNEY PROXIMAL TUBULAR CELLS 172
PERITUBULAR MEMBRANE POTENTIAL IN SODIUM MALEATE-TREATED FROG KIDNEY PROXIMAL TUBULAR CELLS 178
PROSTAGLANDIN ACTION ON RENAL PROXIMAL TUBULE AS REVEALED BY ELECTRICAL STUDIES OF Na+-GLUCOSE COTRANSPORT 186
IV. ACID BASE REGULATION 194
FAILURE OF THE KIDNEY TO OXIDIZE FATTY ACIDS DURING DIABETIC KETOACIDOSIS 194
A ROLE FOR ALANINE BIOSYNTHESIS BY THE KIDNEY 200
EFFECT OF GLUCOCORTICOIDS AND METABOLIC ACIDOSIS ON THE LEVEL OF RAT RENAL PHOSPHOENOLPYRUVATE CARBOXYKINASE mRNA 206
STUDIES ON THE ROLE OP γ-GLUTAMYLTRANSFERASE IN GLUTAMINE METABOLISM IN RAT PROXIMAL TUBULES 214
HIPPURATE SYNTHESIS BY RAT KIDNEY CORTEX SLICES 222
PROLIFERATION OF THE ENDOPLASMIC RETICULUM OF THE PROXIMAL NEPHRON CELLS DURING CHRONIC METABOLIC ACIDOSIS AND AFTER TREATMENT W 228
LIVER AND pH HOMEOSTASIS: REGULATORY MECHANISMS 236
ROLE OF ACID-BASE IN THE REGULATION OF UREA SYNTHESIS 246
IMPORTANCE OF THE GLUTAMATE DEHYDROGENASE PATHWAY IN ALDOSTERONE STIMULATED AMMONIAGENESIS 252
ORGAN SPECIFICITY OF GLUTAMINE HYDROLYSIS AND OXIDATION 260
THE STIMULATION OF THE RESPIRATION OF GLUTAMINE BY RAT RENAL MITOCHONDRIA IN CHRONIC METABOLIC ACIDOSIS 266
HOW HYDROGEN ION HOMEOSTASIS REGULATES PROXIMAL TUBULAR REABSORPTION IN THE DOG KIDNEY 272
ROLE OF RENAL OXYGEN CONSUMPTION RATE IN THE ADAPTIVE AMMONIAGENESIS OF ACIDOSIS 278
RENAL ADAPTATION TO LACTIC ACIDOSIS IN THE DOG 284
VALPROATE DOES NOT STIMULATE RENAL ANMCNIAGENESIS IN THE DOG IN VITO 292
V. ACTION OF DRUGS AND RENAL ADENYLATE METABOLISM 292
METABOLIC EFFECTS OF VALPROATE ON DOG THICK ASCENDING LIMBS 296
ACCELERATION OF AMMONIAGENESIS IN ISOLATED RAT KIDNEY TUBULES BY THE ANTIEPILEPTIC DRUG: VALPROIC ACID 302
SUBSTRATE-DEPENDENT EFFECT OF GENTAMICIN ON GLUCOSE FORMATION IN ISOLATED RABBIT KIDNEY-CORTEX TUBULES 308
URINARY ENZYMES IN PREMATURE INFANTS ¡RELATION TO GENTAMICIN THERAPY 314
CHARACTERIZATION OF A SOLUBLE 5'-NUCLEOTIDASE OF RAT KIDNEY 320
DIFFERENCES IN ADENYLATE METABOLISM IN RENAL CORTEX AND MEDULLA 326
STUDIES ON THE ROLE OF GLYCEROPHOSPHORYLCHOLINE AND SORBITOL IN RENAL OSMOREGULATION 336
VI. PATHOBIOCHEMICAL MODELS 336
LIPID PEROXIDATION, AN INITIAL EVENT IN ACUTE RENAL FAILURE (ARF) 344
SPECIFIC FRUCTOSE-1,6-BISPHOSPHATASE ACTIVITIES IN MICRODISSECTED PROXIMAL TUBULES OF HUMAN KIDNEYS IN FUNCTION AND DYSFUNCTION 354
INTRANEPHRON DISTRIBUTION AND PROPERTIES OF XANTHINE OXIDASE, SUPEROXIDE DISMUTASE AND GUANASE ACTIVITIES IN CONTROL AND NEPHROT 362
CONTRASTING EFFECTS OF AMINO ACID MIXTURES ON HYOPXIC DYSFUNCTION IN THE RAT KIDNEY 368
11β — HYDROXYATEROID DEHYDROGENASE (11- HSD) — ITS FUNCTION IN RENAL CORTICOSTEROID METABOLISM 376
TAMM-HORSFALL PROTEIN AND ANTIBODIES TO TAMM-HORSFALL PROTEIN IN THE STUDY OF RENAL DISEASES 384
STUDIES ON THE RENAL KALLIKREIN-KININ SYSTEM 392
VII. RENAL KALLIKREIN-KININ-SYSTEM, DEVELOPMENTAL ASPECTS OF RENAL METABOLISM 392
RELATION BETWEEN THE RENAL ANGIOTENSIN I CONVERTING ENZYME (CE) AND THE IN ACTIVATION OF KININS BY THE KIDNEY 400
HORMONAL REGULATION OF POSTNATAL DEVELOPMENT OF RENAL TUBULAR TRANSPORT PROCESSES 406
REGULATION OF URIC ACID SYNTHESIS IN EMBRYONIC LIVER AND KIDNEY 412
ROLE OF ADRENAL STEROIDS IN THE MATURATION OF FETAL RAT KIDNEY Na-K-ATPase 418
LIST OF PARTICIPANTS 426
AUTHOR INDEX 430
SUBJECT INDEX 432

Author's affiliation

Walter G. Guder: Mannheim, Germany

Biochemical Aspects of Kidney Function. Proceedings of the 8th International Symposium, Dubrovnik, Yugoslavia, October 5–8, 1986

Description

TOC

Reviews (0)

Author's affiliation