Advances in Integrative Dermatology

Description

An authoritative overview of contemporary approaches to integrative skin health

The popularity of integrative medical treatment of skin disorders has increased significantly in recent years—requiring practicing clinicians to keep pace with continuingdevelopments in dermatological research and methods. Advances in Integrative Dermatology offers a comprehensive survey of this dynamic field, providing up-to-date information on both preventative and therapeutic approaches to skin health. Combining clinical medicine with complimentary treatment plans, integrative dermatology provides an innovative perspective to individual patient care.

This essential text explores new research in areas including the effects of stress and pollution on the skin, the importance of high-quality sleep, complementary methods of averting skin conditions, and more. Recognizing the impact skin disorders have on physiological, psychological, and emotional health, editors Katlein França and Torello Lotti illustrate key components of inclusive skin health strategies, such as therapeutic diets and nutritional supplements, topical botanicals, and other complementary therapies. Filling a significant gap in current literature on integrative dermatology, this valuable resource:

Answers the common questions asked by patients in real-world dermatology practices
Addresses pervasive misconceptions of integrative dermatological methods and principles with evidence-based review of current practices
Examines contemporary research in the diagnosis and treatment of dermatological disorders
Presents comprehensive treatment options for a wide range of conditions such as rosacea, melanoma, and psoriasis

Advances in Integrative Dermatology is an indispensable volume for physicians seeking to incorporate holistic techniques into their practices, expand their knowledge of integrative medicine, and provide the best possible care for their patients.

Title Page 6
Copyright Page 7
Contents 8
Acknowledgements 12
Chapter 1 Advances in Integrative Dermatology: Modifying the Concepts from the Past to Change the Future of Dermatology 20
- Introduction 20
- Integrative Dermatology: Conventional and Complementary Dermatology 21
  - Conventional Dermatology 21
  - Complementary Dermatology 21
- Pillars of the Integrative Approach 21
  - Physical Findings 21
  - Biological Factors: The Psycho-Neuro-Endocrine-Immune System 23
  - Psychological Aspects: Psychodermatology and Quality of Life 23
  - Social Perspective: Social Interactions that Worsen or Improve Patient’s Lives 24
  - Environmental Overview: The Ecology and the Skin 25

Title Page 6
Copyright Page 7
Contents 8
Acknowledgements 12
Chapter 1 Advances in Integrative Dermatology: Modifying the Concepts from the Past to Change the Future of Dermatology 20
- Introduction 20
- Integrative Dermatology: Conventional and Complementary Dermatology 21
  - Conventional Dermatology 21
  - Complementary Dermatology 21
- Pillars of the Integrative Approach 21
  - Physical Findings 21
  - Biological Factors: The Psycho-Neuro-Endocrine-Immune System 23
  - Psychological Aspects: Psychodermatology and Quality of Life 23
  - Social Perspective: Social Interactions that Worsen or Improve Patient’s Lives 24
  - Environmental Overview: The Ecology and the Skin 25
- Conclusion 25
- References 25
Chapter 2 Psycho-Neuro-Endocrine-Immunology: A Psychobiological Concept 28
- Bidirectional PNEI Cross-talk in Dermatology: The Gut–Brain–Skin Axis 29
- Alteration of PNEI Homeostasis, Inflammation, and Dermatologic Diseases 31
- Low-Dose Medicine (LDM): Theoretical, Physiological, and Biochemical Bases 33
- Low-Dose Medicine and Skin Diseases: Preclinical Studies 35
- Low-Dose Medicine and Skin Diseases: Clinical Results 38
- Conclusion 39
- References 39
Chapter 3 Psychoneurocutaneous Medicine 44
- Introduction 44
- Classification of Psychodermatological Diseases 45
- Trichotillomania (Hair-Pulling Disorder) 46
- Dermatitis Artefacta 46
- Delusions of Parasitosis 46
- Obsessive-Compulsive Disorder 47
- Excoriation (Skin-Picking) Disorder 47
- Conclusion 48
- Psychogenic Pruritus 48
- Management Guidelines 48
- References 49
Chapter 4 Acne 52
- Introduction and Epidemiology 52
- Clinical Features and Classification 53
- Perspective of Multifactorial Etiopathogenesis and Relevance of an Integrative Approach 57
  - The Sebaceous Gland: Sebum Synthesis and Acne – An Overview 57
  - Propionibacterium acnes 57
  - Disorder of Follicular Keratinization 58
  - Innate and Adaptive Immunity 58
  - Androgens 58
  - Endocannabinoids 59
  - CRH-ACTH: Cortisol Axis, Psychological Stress, and Acne 59
  - Diet, Lifestyle Habits, and Environmental Factors 59
  - Genetics 61
- Psychopathology and Quality of Life Impairment: An Overview 61
- Assessment of Patients with Acne 63
- Management 66
  - Conventional Topical and Oral Treatment 66
  - Physical Modalities 68
  - Diet, Lifestyle Habits and Environmental Factors 69
  - Psychological Interventions 69
  - Other Complementary Treatments 70
- References 71
- Conclusion 71
Chapter 5 Rosacea 76
- Risk Factors and Triggers 76
- Introduction and Epidemiology 76
- Quality of Life 77
- Associated Diseases 77
  - Digestive Diseases 77
  - Cardiovascular Diseases 77
  - Neurological Diseases 77
  - Metabolic Diseases 77
  - Autoimmunity 78
  - Depression and Anxiety 78
- Pathogenesis 78
- Clinical Variants 78
- Imagistic Approach 79
- Local Treatment 81
- Approach 81
  - Trigger Avoidance 81
  - Makeup 81
  - Photo Protection 81
  - Cosmetics 81
- General Treatment 82
- Laser Treatment 84
- Complementary Medicine 84
- Rosacea Management 85
- References 86
Chapter 6 Seborrheic Dermatitis 90
- Introduction and Epidemiology 90
- Pathogenesis 91
  - Sebaceous Gland Activity 91
  - Immune Response 91
  - Malassezia Colonization 91
  - Other Factors 92
- Psychological Aspects 92
- Clinical Presentation 93
- Diagnosis 94
- Treatment 95
  - Scalp Seborrheic Dermatitis 95
  - Non-scalp Seborrheic Dermatitis 96
  - Emerging/Alternative Therapies 97
- Conclusion 98
- References 100
Chapter 7 Autoimmune Skin Disorders 108
- Introduction 108
- Lupus Erythematosus 109
- Scleroderma 110
- Collagen Vascular Skin Disorders 110
- Pemphigus Vulgaris 111
- Dermatomyositis 111
- Alopecia Areata 113
- Other Inflammatory Skin Disorders 114
  - Psoriasis 114
  - Atopic Dermatitis 115
- Focus on Nonconventional Treatments 116
- References 118
Chapter 8 Vitiligo 122
- Introduction 122
- Pathobiology 125
- Genetics of Vitiligo 125
- Epigenetics in Vitiligo – The Importance of Environmental Factors 125
- Health-Related Quality of Life 127
  - Intimacy and Sexual Dysfunction 127
  - Social Aspects 127
  - Depression and Suicidal Ideation 127
  - Vitiligo as a Social Stigma 127
  - Self-Perception 127
- Treatment 127
  - General Remarks 127
  - Skin Care 128
  - Treatment Goals 128
  - Medical Treatment and Phototherapy 128
  - Lifestyle Intervention 128
  - Alternative Treatments 131
- References 132
Chapter 9 The Combined Approach to Atopic Dermatitis 138
- Introduction 138
- Program for Adults and Older Children 140
  - Stage One: The First Visit – Assessment 140
  - Stage Two: The Second Visit – Instruction 142
  - Stage Four: Follow Up 143
  - Stage Three: Review 143
- Treatment Outcome with Program for Adults and Older Children 144
- Program for Younger Children and Their Parents 144
  - Stage One: Assessment 144
  - Stage Four: Follow-Up Plan 145
  - Stage Two: Instruction 145
  - Stage Three: Review 145
- Treatment Outcome with Program for Younger Children and their Parents 146
  - A Mother’s Story 146
- References 147
- Delivering the Combined Approach for AD 147
- Conclusion 147
Chapter 10 Psoriasis 150
- Introduction 150
- Genetics of Psoriasis 152
- Metabolomics and Microbiome 153
- Epigenetics in Psoriasis – The Importance of Environmental Factors 153
- Health-Related Quality of Life 154
  - Intimacy and Sexual Dysfunction 154
  - Physical Complaints in Psoriasis 154
  - Depression and Suicidality 155
  - Social Aspects 155
- Treatment 155
  - Lifestyle Intervention 156
  - Skin Care 156
  - Treatment Goals 156
  - Alternative Treatments 157
  - Medical Treatment and Phototherapy 157
- References 158
Chapter 11 Urticaria 164
- Introduction 164
- Major Cells, Mediators, and Immunopathogenesis of Urticaria 165
  - Mast Cells 165
  - Basophils 165
  - Eosinophils 166
  - Histamine 166
  - Other Cytokines and Chemokines 167
  - Pentraxin 3 (PTX3) 167
  - Proinflammatory Cytokines 167
  - C-Reactive Protein (CRP) 167
  - Immunopathogenesis of Urticaria 168
- Etiology and Pathology of Urticaria 165
- Endothelium and Coagulation System in CSU 169
- Role of Autologous Serum Skin Test (ASST) 169
- Role of Angiogenesis in CSU 170
- Therapy 171
- Diagnosis 171
- References 173
Chapter 12 Lichen Planus and Lichenoid Disorders 182
- Introduction 182
- Clinical Manifestations 183
- Pathogenesis 183
- Emotional and Mental Aspects 184
- Treatment 185
  - Topical Therapies 185
  - Conventional and Emerging Therapies 185
  - Systemic Therapies 187
- Diagnosis 185
- Complementary and Alternative Treatments 190
  - Hygiene 190
  - Dietary Modifications 190
  - Topical and Oral Herbal Medications 190
  - Vitamin Supplements 191
  - Mind–Body Approaches 191
  - Traditional Chinese Medicine 192
  - Ayurveda 192
- Lichenoid Reactions 192
  - Lichenoid Drug Eruptions 193
  - Management 194
- Conclusion 195
- Oral Lichenoid Contact Reactions 195
  - Etiology, Pathogenesis, and Clinical Manifestation 195
  - Management 195
- References 196
Chapter 13 Itch: An Integrative Approach 206
- Introduction 206
- Definition and Classification 207
- Epidemiology and Clinical Features 208
  - Population-Based Studies 208
  - Cutaneous Disorders 209
  - Systemic Disorders 212
- Pathogenesis 213
- Burden of the Disease 216
- Diagnosis 217
- Treatment 219
  - General Recommendations 219
  - Topical Therapy 220
  - Phototherapy 222
  - Systemic Therapy 223
  - NK1R-Antagonists 226
  - Thalidomide 227
  - Mu-Opioid Antagonists and Kappa-Opioid Agonists 227
  - Antiepileptic Drugs 228
  - Biologic Drugs 229
  - Miscellaneous 229
  - Apremilast 229
- Conclusion 230
- References 230
Chapter 14 Infections of the Skin 250
- Infections of the Skin Caused by Bacteria 250
  - Physical Aspects 250
  - Environmental Changes and Their Impact 251
  - Emotional, Mental, and Social Aspects 251
  - Relationship with Stress 252
  - Treatment 253
- Infections of the Skin Caused by Viruses 253
  - Emotional, Mental, and Social Aspects 253
  - Physical Aspects 253
  - Treatment 254
  - Environmental Changes and Their Impact 254
  - Relationship with Psychosocial Stress 254
- Infections of the Skin Caused by Fungi 256
  - Physical Aspects 256
  - Emotional, Mental, and Social Aspects 257
  - Relationship with Psychosocial Stress 258
  - Treatment 258
  - Environmental Changes and Their Impact 258
- Infections of the Skin Caused by Parasites 259
  - Physical Aspects 259
  - Emotional, Mental, and Social Aspects 259
  - Environmental Changes and Their Impact 260
  - Relationship with Psychosocial Stress 261
  - Treatment 261
- Infections of the Skin Caused by Mycobacteria 262
  - Physical Aspects 262
  - Emotional, Mental, and Social Aspects 262
  - Treatment 264
  - Environmental Changes and Their Impact 264
  - Relationship with Psychosocial Stress 264
- Sexually Transmitted Infections 266
  - Physical Aspects 266
  - Emotional, Mental, and Social Aspects 267
  - Environmental Changes and Their Impact 267
  - Treatment 268
  - Relationship with Psychosocial Stress 268
- References 269
Chapter 15 Nonmelanoma Skin Cancer 276
- Introduction 276
- Etiology 276
- Basal Cell Carcinoma (BCC) 277
  - Histopathology of BCC 277
  - Etiology 277
  - Clinical Features 277
- Squamous Cell Carcinoma (SCC) 278
  - Clinical Features 278
  - Histopathology of SCC 279
  - Role of Sunscreen Agents 279
- Management 279
  - Excision with Predetermined Margins 279
  - Cryosurgery 280
  - Radiotherapy 280
  - Curettage and Cautery (C&&C) 280
  - Mohs Micrographic Surgery (MMS) 280
  - 5-Fluorouracil (5FU) 281
  - Photodynamic Therapy 281
  - Hedgehog Inhibitors 281
  - Imiquimod 281
  - Botanical Therapy 281
- Psychological Aspects of NMSC 282
- References 283
- Conclusion 283
Chapter 16 Melanoma 290
- Introduction 290
- Epidemiology 291
  - Trends in Melanoma Mortality 292
- Three Roots of Melanoma 292

Description

TOC

Reviews (0)